This month, the American Journal of Psychiatry published a research article that concluded that anti-depressant medication’s are not nearly as effective as they claim to be.
The first baffling thing that the reporting research scientists found was: the testing done to determine the ability of anti-depressants in treating depression is carried out on groups of people who are not at all like the typical every day person prescribed an anti-depressant.
Let me explain.
Basically, to get a drug approved and out to the general population, it must go through what are called phase III clinical trials. These trials determine a drug’s efficacy on a group of individuals who meet certain criteria determined by the researchers. The study published in the American Journal of Psychiatry has determined that the chosen group of individuals used to test anti-depressants like Celexa is not a true representation of the general population who are prescribed these drugs.
Here’s another thing the researchers uncover: the efficacy of antidepressants in those who did not meet phase III inclusion criteria – meaning the majority of the real world people who take antidepressants – are not nearly as effective as once thought.
Probably because they are being tested on the wrong people!?!
Bottom line: antidepressants aren’t very effective at all.
Check out the science behind this research: Can phase III trial results of antidepressant medications be generalized to clinical practice?